Natural Resistance–Associated Macrophage Protein 1 Polymorphisms Are Associated with Microscopy‐Positive Tuberculosis
نویسندگان
چکیده
منابع مشابه
natural resistance associated macrophage protein 1 gene polymorphism is associated with chronic periodontitis not peri-implantitis in an iranian population: a cross sectional study
in inflammatory diseases such as peri-implantitis (pi) and chronic periodontitis (cp) both adaptive and innate immunity play a part. natural resistance associated macrophage protein 1 ( nramp1 ) has considerable effects on macrophage function (phagocytosis) and host innate immune response against infections. the present study was to investigate the relationship of nramp1 gene polymorphisms with...
متن کاملUncoupling protein 2 gene polymorphisms are associated with obesity
BACKGROUND Uncoupling protein 2 (UCP2) gene polymorphisms have been reported as genetic risk factors for obesity and type 2 diabetes mellitus (T2DM). We examined the association of commonly observed UCP2 G(-866)A (rs659366) and Ala55Val (C > T) (rs660339) single nucleotide polymorphisms (SNPs) with obesity, high fasting plasma glucose, and serum lipids in a Balinese population. METHODS A tota...
متن کاملPolymorphisms in IGF-binding protein 1 are associated with impaired renal function in type 2 diabetes.
The dysregulation of the IGF system has been implicated in the pathogenesis of obesity, diabetes, and diabetes complications such as nephropathy, but little is known about the genomics of the IGF system in health and disease. We genotyped 13 single nucleotide polymorphisms (SNPs) in IGFBP1 gene in 732 representative type 2 diabetic patients from the Salford Diabetes Register. Of the 13 SNPs, 8 ...
متن کاملNatural-resistance-associated macrophage protein 1 is an H+/bivalent cation antiporter.
In mammals, natural-resistance-associated macrophage protein 1 (Nramp1) regulates macrophage activation and is associated with infectious and autoimmune diseases. Nramp2 is associated with anaemia. Both belong to a highly conserved eukaryote/prokaryote protein family. We used Xenopus oocytes to demonstrate that, like Nramp2, Nramp1 is a bivalent cation (Fe2+, Zn2+ and Mn2+) transporter. Strikin...
متن کاملNatural resistance-associated macrophage protein 1 gene polymorphisms and response to vaccine against or challenge with Salmonella enteritidis in young chicks.
Salmonella enteritidis (SE) contamination of poultry products is of global food-safety concern. The natural resistance-associated macrophage protein 1 (NRAMP1) affects host innate immunity to intracellular bacteria because of its ability to transport divalent cations in late endosome/lysosomes. Studying the association of the NRAMP1 gene and chicken innate immune response to SE can, therefore, ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2002
ISSN: 0022-1899,1537-6613
DOI: 10.1086/341775